Autosomal dominant polycystic kidney disease

Kidney with Polycystic Disease

ADPKD Most Common

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease.  About 12.5 million people worldwide and is the cause of 10% of End-Stage Kidney Disease (ESRD) that requires dialysis. It is the most common hereditary disorder that affects the kidneys.

Kidney-Friendly Foods

Nutrition is important for everyone and eating a kidney-friendly diet for those that have ADPKD may help slow growth of cysts and slow the course of kidney function decline. 

Parent to Child

It's passed to 50% of the children from an affected parent. Polycystic means 'many cysts' and, for those with the disease, their kidneys can become very large and have a bumpy surface made of fluid-filled cysts.

Keeping Pressure Down

When cysts expand, this causes pressure to the kidney tissue which, may lead to end-stage kidney failure.

For those with the disease by their mid 40's dialysis and or transplantation are often required.  Remember that kidney function decline is different in each person with ADPKD. Important to remember to have your blood pressure and overall health followed closely by your doctor.

Seek Advice

Since this is inherited, people with the disease should seek advice in informing and testing family members who may be affected. Your social worker can advise you regarding the implications of life insurance and private insurance.

MRI scan of the abdomen showing polycystic disease of the kidneys

What Are the Most Common Complications of ADPKD?

Those that suffer with ADPKD have pain, high blood pressure, and kidney failure at some point in their lives.

Pain

Pain is a common complication of ADPKD and is usually due to kidney or liver cysts. Pain also can be caused by:

  • kidney cyst infection
  • bleeding or burst kidney cysts
  • urinary tract infection
  • kidney stones
  • tissue stretching around the kidney due to cyst growth

Additional side effects of ADPKD includes high blood pressure, edema, acidosis, heart health, stroke and kidney stones.  

While there is no cure for PKD, recent clinical studies in adults have identified therapies that can slow the progression of the kidney disease. These therapies are not yet available for children.

Recommended Topics

Kids   |  Common Causes

Reflux 

Often after a child has had a urinary tract infection Reflux may be diagnosed.

Kids   |  Common Causes

Urinary Tract Infection

If the UTI involves the kidneys, fever and back pain may also occur.

Kids   |  Symptoms

Symptoms & Signs

The signs of kidney disease are subtle and silent. Kidney disease can strike at any age.

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The Kidney-Friendly Ultimate Grocery List with brand names you know & love.

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The Kidney-Friendly Ultimate Grocery List with brand names you know and love is helpful when food shopping. 

We've included a couple of kidney-friendly recipes that are easy to make and tasty and most importantly kidney-friendly!